لینک دانلود و خرید پایین توضیحات
دسته بندی : پاورپوینت
نوع فایل : powerpoint (..PPT) ( قابل ويرايش و آماده پرينت )
تعداد اسلاید : 51 اسلاید
قسمتی از متن powerpoint (..PPT) :
Complement functions
Host benefit:
opsonization to enhance phagocytosis
phagocyte attraction and activation
lysis of bacteria and infected cells
regulation of antibody responses
clearance of immune complexes
clearance of apoptotic cells
Host detriment:
Inflammation, anaphylaxis
سيستم كمپلمان شامل پروتئينهاي پلاسمايي و غشايي مي باشد كه با يكديگر و با ساير مولكولهاي سيستم ايمني واكنش مي دهند
اين سيستم بوسيله ميكروبها و يا آنتي باديهايي كه به ميكروبها وساير آنتي ژنهاچسبيده اندفعال مي شود
فعال شدن اين سيستم بوسيله پروتئينهاي تنظيمي كه در سطح سلولهاي طبيعي ميزبان وجود دارند مهارمي شود
2
Proteins of the complement system (nomenclature)
C1(qrs), C2, C3, C4, C5, C6, C7, C8, C9
factors B, D, H and I, properdin (P)
mannose binding lectin (MBL), MBL associated serine proteases (MASP-1 MASP-2)
C1 inhibitor (C1-INH, serpin), C4-binding protein (C4-BP), decay accelerating factor (DAF), Complement receptor 1 (CR1), protein-S (vitronectin)
Activation product of complement proteins (nomenclature)
When enzymatically cleaved, the larger moiety , binds to the activation complex or membrane and the smaller peptide is released in the microenvironment
Letter “b” is usually added to the larger, membrane-binding, peptide and “a” to the smaller peptide ( e.g. , C3b/C3a, C4b/C4a, C5b/C5a), EXCEPT C2 (the larger, membrane-binding moiety is C2a; the smaller one is C2b)
Activated component are usually over-lined: e.g. C1qrs
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پاورپوینت Complement functions Complement functions دانلود پاورپوینت Complement functions Complement functions پاورپوینت Complement functions